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Buy melatonin without prescription, Since bottoming near the end of 2008, ISIS Pharmaceuticals has been one of the hottest stocks in the first half of 2009. Melatonin no prescription, In fact, in just a few short months, discount melatonin overnight delivery, Order cheap melatonin online, the stock has exhibited all the tell tale signs of a powerful, interim trend reversal, canadian melatonin. Buy melatonin overnight delivery, More importantly, a look at ISIS's 3-year weekly chart shows that despite a dramatic correction in 2008, melatonin no rx, Melatonin order, the stock maintained its long term, continuum with a swift reversal off of its 200-week moving average (shown below).
Profound bullish action in the first half of 2009 culminated in the stock's recent acceleration from $15/share to nearly $19/share in advance of earnings last week, buy melatonin on line. Buy melatonin online, Unfortunately, exuberance seems to have over shot a bit and, buy melatonin no rx, Buy melatonin without prescription, despite a relatively strong earnings report, the stock has sold off in recent sessions, buy melatonin low price. Buy melatonin once daily, Could that spell an opportunity for bargain hunting investors to jump aboard?
What is Isis Pharmaceuticals?
Isis Pharmaceuticals is a drug discovery and development company which is the leading researcher in the field of antisense therapies. Antisense is a treatment for genetic disorders which focuses on the use of specially coded nucleic strands to bind to mRNA within a patient's cells, buy melatonin without prescription. For those of you who remember high school biology class, melatonin sales, Cheap melatonin tablets, mRNA is the nucleic acid which carries coding information from the nucleus to the ribosomes for protein synthesis. A sense is a single sequence which codes for a particular protein, melatonin pills. Cheapest melatonin, Antisense therapies focus on suppressing expression of a particular sense which effectively "turns off" particular genes.
Antisense drugs are a new class of pharmaceuticals and have the potential to change the way diseases are treated, find no rx melatonin. Buy melatonin without prescription, Since these drugs are highly specific, targeting individual proteins being coded by RNA, they represent a large step towards more personalized medicine and theoretically should reduce unwanted side-effects in comparison to traditional protein or small-molecule pharmaceuticals. Melatonin online without a prescription, Moreover, since all antisense treatments utilize the same basic functionality - the delivery of an antisense molecule to target a specific RNA sequence - development times for new drugs can be shortened as early stage responses are more predictable.
Isis was the first biotech firm to bring an antisense therapy to market (Vitravene in 1998) and is a market leader in the manipulation and research of RNA.
Liquidity and Profitability
Isis reported $638 million in cash in its last filing and expects to burn roughly $90 million in cash over the course of the year, melatonin alternative. Melatonin without a prescription, At current cash burn rates, the Company should be more than able to finance the development of its more promising drugs without needing to access capital markets over the next few years, melatonin medication. Melatonin buy online, A good thing given the current environment for both debt and equity capital.
Consensus estimates have the Company losing roughly 30 cents per share in 2010, cost melatonin. The Company's drug pipeline includes 19 drugs in development either by Isis or in partnership with another pharmaceutical, but its most promising drug, Mipomersen (a drug for the treatment of high cholesterol in development with Genzyme), is not likely to be filed with the FDA until late 2010.
Investment Thesis
As with many smaller biotech firms, Isis does not have a large portfolio of on patent, in-the-market drugs and the stock today trades on the expectation of profitability as opposed to real earnings power, buy melatonin without prescription. Buy cheap melatonin, Isis benefits, however, cheap melatonin overnight delivery, Order melatonin no rx, from consistent research and development revenues as a result of partnerships with larger pharmaceuticals. Antisense and gene therapies in general represent the next generation of pharmaceuticals and are of particular interest to big pharma which faces dwindling patent protections and uninspired drug pipelines, cheap melatonin in usa. Order melatonin from canada, Isis' track record as the only biotech to bring an antisense drug to market as well as the current co-developer of a phase III cholesterol drug which could receive FDA approval by 2010 makes it a particularly coveted partner (and potential acquisition candidate). With the Company's long term stock trend in tact and intermediate stock action showing resilience near its 50-day moving average, melatonin information, Melatonin overnight, I'm ready to jump in on this stock as a speculative buy with a target in the low-$20s.
Full Disclosure: Long shares of ISIS at the time of writing, order melatonin no prescription. Melatonin online review, . Buy melatonin in canada. Cheap melatonin without prescription. Buy melatonin online cheap. Buy melatonin canada. Melatonin drug. Melatonin rx. Melatonin free sample.
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[...] recently highlighted a small biotech firm, ISIS Pharmaceuticals, as a potential “value” growth pl…. ISIS took a tumble after earnings despite being just a penny off of estimates. Despite slightly [...]